Denmark takes first place in second annual World Citizenship Report, global ‘powerhouses’ lose their lustre among the mass affluent

London, United Kingdom, April 20, 2023 (GLOBE NEWSWIRE) — Denmark, Switzerland and Finland took the top three spots in the 2023 World Citizenship Report, which launched today. The World Citizenship Report ranks 188 countries across five key motivators defining citizenship for the global citizen.

Published by CS Global Partners, the world’s leading government and investment migration advisory firm, the World Citizenship Report showcases the World Citizenship Index (WCI), an innovative tool that takes a holistic approach to rank the world’s citizenships across multiple dimensions including the motivators of Safety and Security, Quality of Life, Economic Opportunity, Global Mobility and Financial Freedom.

The World Citizenship Index is the product of a research-driven approach that goes beyond ordinary concepts of passport strength by placing greater emphasis on the diverse attitudes regarding key facets of citizenship. Unlike other rating tools, the World Citizenship Index ranking is designed to reflect a citizenship’s value through the lens of high-net-worth-individuals (HNWIs) and the newest generation of global citizens: the mass affluent population.

“This year, we looked beyond HNWIs and extended our survey to the new mass affluent, a globally mobile generation who is providing fresh impetus for a renewed drive towards global citizenship. As the world around continues to change at an exponential rate, bringing with it new crises and opportunities – individuals across the globe are increasingly calling their own citizenships into question in terms of the safety, freedoms, and the prosperity they provide,” said Micha Emmett, CEO of CS Global Partners.

“This Report stands apart from other reports in the industry because it examines which countries offer the most benefits for global citizens, particularly in a post-COVID world where those that have the means are consistently searching for greater opportunities.”

This year, Denmark kicked Switzerland out of the top spot and scored the highest points. Switzerland ranked in second place and Finland retained the third spot for a second year in a row.

Notably, global superpowers such as the United States and China did not rank in the top ten, symbolising a significant shift in what these economic giants can tangibly offer the global elite. HNWIs and mass affluent citizens are searching for a better quality of life, security and financial freedoms, all aspects which have been on shaky ground since the pandemic.

The surveyed cohort chose ‘Quality of Life’ as the most important feature of citizenship, which ranked first across the World Citizenship Index’s five pillars, eclipsing both Physical Safety and Financial Freedom.

The Report found that a competitive economy, public services, and environmental sustainability are the three areas mass affluent individuals feel most let down by their governments.​

We are unfortunately living through a period where the standard of living is falling at the fastest rate in over a generation. At the end of 2022, the UK Office for Budget Responsibility reported that UK households are set to suffer a 7.1 per cent fall in living standards over the next two years, the largest decline in six decades. Furthermore, according to the latest United Nations Development Programme (UNDP) report published in the same period, living conditions in 90 per cent of the world’s countries deteriorated in 2021 – something that hasn’t been seen since the height of the previous global recession caused by the financial crisis in 2007. Moreover, the UNDP report marked the first consecutive year of decline in the 32-year history of the Human Development Index (HDI) – these trends are reflected in the current World Citizenship Index scores. For example, the United States dropped to 29th position for the Quality-of-Life motivator from 20th position previously, which shows how living standards are coming under pressure even in the world’s economic powerhouses.

“The World Citizenship Report aims to capture what truly concerns and affects a global citizen,” added Emmet. “When there are options to gain a second or third citizenship, the first question in a HNWIs mind is ‘where is the next place to be associated with?’”

“High-net-worth individuals and the mass affluent must consider a myriad of factors when deciding something as monumental as where to obtain second citizenship and build a second home. While passport strength is, of course, an important component, it is also one that is subject to the greatest change as evidenced by pandemic related travel restrictions,” she added.

As many parts of the globe recover from COVID-19 and find means to bolster their economies, a new chain of threats has emerged. The conflict in the Ukraine has not only made many nations in the northern hemisphere realise just how fragile the concept of safety and freedom is but has severely impacted energy and food security across the world.

With so much change happening so rapidly around us, it can be challenging to keep up with how all these disparate factors coming to bear on the prevailing attitudes toward global citizenship. And this is where the value of the World Citizenship Report comes into the picture. The Report continues to build on its reputation as an ambitious product reflecting the evolving nature of these attitudes toward citizenship, and one that is in tune with the defining issues of our time with respect to global citizens, including health and wellbeing, environmental sustainability, and shifting investment priorities.

The World Citizenship Index’s unique methodology relies on the experience gained through CS Global Partners unparalleled work in the citizenship solutions industry, as well as comprehensive research to evaluate 188 jurisdictions across the five motivators of citizenship out of a maximum attainable score of 100 points.

The Report’s multidimensional approach ensured that the attitudes under investigation were captured as accurately and meaningfully as possible. Consequently, rather than relying exclusively on value judgments to construct and weight the World Citizenship Index, CS Global Partners also leveraged its unparalleled network of industry experts and access to global citizens to isolate the major motivations for attaining a second citizenship. These factors were then further explored and validated by surveying the global mass affluent population on the value of second citizenship.

Thembi Saleshando
CS Global Partners
+44 (0) 207 318 4343
Thembi.Saleshando@csglobalpartners.com

GlobeNewswire Distribution ID 8812232

The Prestigious U.S. Open Polo Championship Returns to the USPA National Polo Center, Sunday, April 23

Final Competition of the U.S. Polo Season to Air on ESPN Platforms

WELLINGTON, FL / ACCESSWIRE / April 20, 2023 / U.S. Polo Assn. and the United States Polo Association (USPA) are proud to host the U.S. Open Polo Championship® on Sunday, April 23, at the number one destination for polo in the United States, the USPA National Polo Center (NPC) – Wellington. While celebrating the heritage and tradition of the sport of polo, the U.S. Open Polo Championship is notably recognized as the most coveted trophy in the United States.

Related Image

https://cdn.newswire.com/files/x/e4/ea/67d901b2d731b4fd934c29d66cd8.jpg

Top Players Facundo Pieres and Juan Britos in the Gold Cup Semi-Finals. Credit Alex Pacheco.

The 2023 Winter Polo Season at NPC has had record attendance, with a waitlist for this year’s U.S. Open Polo Championship game. For those who can’t attend in person, ESPN will air the Championship final for millions of sports fans on ESPN platforms on April 24 at 9:30pm EDT. Check your local listings or click here for local air times and channels.

In the action-packed U.S. Open Polo Championship Final game, the two teams who prevail in their respective games in the semi-finals will then go head to head to ultimately take home the coveted trophy and $100,000. The U.S. Open Polo Championship features the sport’s finest players from around the world, alongside their equine athletes. Globally renowned players on this day could include the number one player in the world, Adolfo Cambiaso as well as 10-goalers Facundo Pieres and Hilario Ulloa.

“The close of a record-breaking season for the sport of polo in the United States is the U.S. Open Polo Championship, which continues to be the sport’s highlight for players and fans alike,” said Stewart Armstrong, Chairman of the USPA. “It’s always exciting to see the top two teams compete for the trophy in the Open and leave it all on the field, this year, with millions of fans watching on site in Palm Beach County and now on ESPN.”

The Winter High Goal Polo Season at NPC has offered sports fans an elevated season which included the Westchester Cup, the oldest rivalry in polo, along with the broadcast of multiple iconic polo tournaments on ESPN platforms, and a special guest appearance by award-winning pop artist @Maluma – all from the Winter Equestrian Capital of the World. This year, fans have been able to purchase custom, branded U.S. Open and Westchester Cup merchandise on site and on uspapro.com.

“U.S. Polo Assn. is proud to partner with the USPA in hosting the most prestigious tournaments, here at NPC, the sport’s premier destination,” said J. Michael Prince, President and CEO of USPA Global Licensing Inc., which manages the multi-billion-dollar U.S. Polo Assn. brand. “Our iconic partnership with ESPN, the world’s leading sport content provider, has brought the sport into millions of households for the very first time. This relationship has been vital to increasing exposure to the sport for the USPA and to demonstrating the authenticity between the U.S. Polo Assn. brand and the sport of polo for consumers around the world.”

“Together with the USPA, The Palm Beaches and our amazing local, national and global sponsors and partners, we look forward to celebrating the U.S. Open Polo Championship winner on Sunday, April 23, and a highly successful 2023 Season,” added Prince.

About U.S. Polo Assn.

U.S. Polo Assn. is the official brand of the United States Polo Association (USPA), the non-profit governing body for the sport of polo in the United States and one of the oldest sports governing bodies, having been founded in 1890. With a multi-billion-dollar global footprint and worldwide distribution through some 1,100 U.S. Polo Assn. retail stores and thousands of department stores as well as sporting goods channels, independent retailers and e-commerce, U.S. Polo Assn. offers apparel for men, women, and children, as well as accessories and footwear in more than 190 countries worldwide. U.S. Polo Assn. was named as one of the top five sports licensors in 2022, according to License Global. Visit uspoloassnglobal.com and follow @uspoloassn.

USPA Global Licensing Inc. (USPAGL) is the for-profit subsidiary of the USPA and its exclusive worldwide licensor. USPAGL manages the global, multi-billion-dollar U.S. Polo Assn. brand and is the steward of the USPA’s intellectual properties, providing the sport with a long-term source of revenue. Through its subsidiary, Global Polo Entertainment (GPE), USPAGL also manages Global Polo TV, which provides polo, sport and lifestyle content. A historic, multi-year, global arrangement has been signed by USPAGL and ESPN for the world’s leading sports content provider to air seven of the top final polo games in the U.S., allowing millions of sports fans and consumers to enjoy the sport across ESPN’s broadcast and streaming platforms. For more sport content, visit globalpolo.com.

About the United States Polo Association® (USPA)

The United States Polo Association was organized and exists for the purposes of promoting the game of polo, coordinating the activities of its Member Clubs and Registered Players, arranging and supervising polo tournaments, competitions and games, and providing rules, handicaps, and conditions for those tournaments, competitions, and games including the safety and welfare of participants and mounts. Founded in 1890, the USPA is the national governing body for the sport of polo. The USPA is currently comprised of almost 200 member clubs with thousands of individual members and oversees 40 national tournaments. For more information, please visit uspolo.org.

Contact Information

Stacey Kovalsky
Senior Director, Global Communications
skovalsky@uspagl.com
+001.561.790.8036

Shannon Stilson
VP, Sports Marketing & Media
sstilson@uspagl.com
+001.561.227.6994

SOURCE: USPA Global Licensing Inc.

MCB INVESTOR NEWS: ROSEN, TOP RANKED GLOBAL COUNSEL, Encourages Metropolitan Bank Holding Corp. Investors to Inquire About Securities Class Action Investigation – MCB

NEW YORK, April 19, 2023 (GLOBE NEWSWIRE) — WHY: Rosen Law Firm, a global investor rights law firm, continues to investigate potential securities claims on behalf of shareholders of Metropolitan Bank Holding Corp. (NYSE: MCB), the holding company for Metropolitan Commercial Bank, resulting from allegations that MCB may have issued materially misleading business information to the investing public.

SO WHAT: If you purchased MCB securities you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement. The Rosen Law Firm is preparing a class action seeking recovery of investor losses.

WHAT TO DO NEXT: To join the prospective class action, go to https://rosenlegal.com/submit-form/?case_id=14239 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action.

WHAT IS THIS ABOUT: On March 30, 2023, market analyst Vidar Research published a report entitled “Metropolitan Commercial Bank is a mixed bag of problems[.]” The report alleged that “[Metropolitan Commercial Bank] is bleeding deposits[,]” stated that Metropolitan Commercial Bank “is the issuer of choice for prepaid debit cards of crypto firms[,]” questioned whether Metropolitan Commercial Bank was actually moving away from cryptocurrency (as it had allegedly announced), and alleged that its balance sheet “is shocking comparable to the failed Signature Bank (SBNY)[.]” In summary, the report alleged that Metropolitan Commercial Bank “is a failed bank and that it will share the fate with the likes of SBNY [Signature Bank] and SIVB [Silicon Valley Bank].”

On this news, MCB’s stock price fell $9.66 per share, or 27.6%, to close at $25.36 per share on March 30, 2023.

WHY ROSEN LAW: We encourage investors to select qualified counsel with a track record of success in leadership roles. Often, firms issuing notices do not have comparable experience, resources, or any meaningful peer recognition. Many of these firms do not actually litigate securities class actions. Be wise in selecting counsel. The Rosen Law Firm represents investors throughout the globe, concentrating its practice in securities class actions and shareholder derivative litigation. Rosen Law Firm has achieved the largest ever securities class action settlement against a Chinese Company. Rosen Law Firm was Ranked No. 1 by ISS Securities Class Action Services for number of securities class action settlements in 2017. The firm has been ranked in the top 4 each year since 2013 and has recovered hundreds of millions of dollars for investors. In 2019 alone the firm secured over $438 million for investors. In 2020, founding partner Laurence Rosen was named by law360 as a Titan of Plaintiffs’ Bar. Many of the firm’s attorneys have been recognized by Lawdragon and Super Lawyers.

Follow us for updates on LinkedIn: https://www.linkedin.com/company/the-rosen-law-firm, on Twitter: https://twitter.com/rosen_firm or on Facebook: https://www.facebook.com/rosenlawfirm/.

Attorney Advertising. Prior results do not guarantee a similar outcome.

Contact Information:

Laurence Rosen, Esq.
Phillip Kim, Esq.
The Rosen Law Firm, P.A.
275 Madison Avenue, 40th Floor
New York, NY 10016
Tel: (212) 686-1060
Toll Free: (866) 767-3653
Fax: (212) 202-3827
lrosen@rosenlegal.com
pkim@rosenlegal.com
cases@rosenlegal.com
www.rosenlegal.com

GlobeNewswire Distribution ID 8811620

ROSEN, GLOBAL INVESTOR COUNSEL, Encourages adidas AG Investors to Inquire About Securities Class Action Investigation – ADDYY, ADDDF

NEW YORK, April 19, 2023 (GLOBE NEWSWIRE) — WHY: Rosen Law Firm, a global investor rights law firm, continues to investigate potential securities claims on behalf of shareholders of adidas AG (OTC: ADDYY, ADDDF) resulting from allegations that adidas may have issued materially misleading business information to the investing public.

SO WHAT: If you purchased adidas securities you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement. The Rosen Law Firm is preparing a class action seeking recovery of investor losses.

WHAT TO DO NEXT: To join the prospective class action, go to https://rosenlegal.com/submit-form/?case_id=12204 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action.

WHAT IS THIS ABOUT: On October 25, 2022, adidas ended its lucrative business partnership with Kanye West (under which it sold products designed by West under the brand name “Yeezy”) as a result of his anti-Semitic rhetoric.

On November 27, 2022, The Wall Street Journal published an article entitled “Adidas Top Executives Discussed Risk of Staff’s ‘Direct Exposure’ to Kanye West Years Ago.” According to the article, as early as 2018, adidas executives discussed ending the business partnership with West as a result of his behavior. Reportedly adidas feared continuing the relationship with West, as they feared it could “blow up” at any moment. The article added that West made anti-Semitic statements in front of adidas staff, and that he told adidas staff that he was considering naming an album after Adolf Hitler.

On February 9, 2023 adidas announced that “while the company continues to review future options for the utilization of its Yeezy inventory, this guidance already accounts for the significant adverse impact from not selling the existing stock. This would lower revenues by around € 1.2 billion and operating profit by around € 500 million this year.” Further, “should the company irrevocably decide not to repurpose any of the existing Yeezy product going forward, this would result in the write-off of the existing Yeezy inventory and would lower the company’s operating profit by an additional € 500 million this year. In addition, adidas expects one-off costs of up to € 200 million in 2023. These costs are part of a strategic review the company is currently conducting aimed at reigniting profitable growth as of 2024. If all these effects were to materialize, the company would expect to report an operating loss of € 700 million in 2023.” adidas’ CEO stated, “[t]he numbers speak for themselves. We are currently not performing the way we should[.]”

As a result of these adverse disclosures the price of adidas securities have fallen, damaging investors.

WHY ROSEN LAW: We encourage investors to select qualified counsel with a track record of success in leadership roles. Often, firms issuing notices do not have comparable experience, resources, or any meaningful peer recognition. Many of these firms do not actually litigate securities class actions. Be wise in selecting counsel. The Rosen Law Firm represents investors throughout the globe, concentrating its practice in securities class actions and shareholder derivative litigation. Rosen Law Firm has achieved the largest ever securities class action settlement against a Chinese Company. Rosen Law Firm was Ranked No. 1 by ISS Securities Class Action Services for number of securities class action settlements in 2017. The firm has been ranked in the top 4 each year since 2013 and has recovered hundreds of millions of dollars for investors. In 2019 alone the firm secured over $438 million for investors. In 2020, founding partner Laurence Rosen was named by law360 as a Titan of Plaintiffs’ Bar. Many of the firm’s attorneys have been recognized by Lawdragon and Super Lawyers.

Follow us for updates on LinkedIn: https://www.linkedin.com/company/the-rosen-law-firm, on Twitter: https://twitter.com/rosen_firm or on Facebook: https://www.facebook.com/rosenlawfirm/.

Attorney Advertising. Prior results do not guarantee a similar outcome.

Contact Information:

Laurence Rosen, Esq.
Phillip Kim, Esq.
The Rosen Law Firm, P.A.
275 Madison Avenue, 40th Floor
New York, NY 10016
Tel: (212) 686-1060
Toll Free: (866) 767-3653
Fax: (212) 202-3827
lrosen@rosenlegal.com
pkim@rosenlegal.com
cases@rosenlegal.com
www.rosenlegal.com

GlobeNewswire Distribution ID 8811744

LPLA INVESTOR NEWS: ROSEN, A GLOBALLY RECOGNIZED FIRM, Encourages LPL Financial Holdings Inc. Investors to Inquire About Class Action Investigation – LPLA

NEW YORK, April 19, 2023 (GLOBE NEWSWIRE) —

WHY: Rosen Law Firm, a global investor rights law firm, announces an investigation of potential securities claims on behalf of shareholders of LPL Financial Holdings Inc. (NASDAQ: LPLA) resulting from allegations that LPL Financial may have issued materially misleading business information to the investing public.

SO WHAT: If you purchased LPL Financial securities you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement. The Rosen Law Firm is preparing a class action seeking recovery of investor losses.

WHAT TO DO NEXT: To join the prospective class action, go to https://rosenlegal.com/submit-form/?case_id=14238 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action.

WHAT IS THIS ABOUT: On March 23, 2023, after market hours, LPL Financial issued a press release entitled “LPL Financial Reports Monthly Activity For February 2023” in which LPL Financial disclosed that its total net new assets plunged 40% to $5.2 billion in February 2023 as opposed to January of 2023. Further, release revealed that LPL Financial’s total advisory and brokerage assets were $1.15 trillion at the end of February 2023, down 1.5% from the end of January 2023. In addition, the release revealed that LPL Financial’s total client cash balances declined from $59.7 billion in January 2023 to $56.2 billion in February 2023, a decline of 5.9%.

On this news, LPL’s stock price fell $11.88 per share, or 5.8%, to close at $192.00 per share on March 24, 2023.

WHY ROSEN LAW: We encourage investors to select qualified counsel with a track record of success in leadership roles. Often, firms issuing notices do not have comparable experience, resources, or any meaningful peer recognition. Many of these firms do not actually litigate securities class actions. Be wise in selecting counsel. The Rosen Law Firm represents investors throughout the globe, concentrating its practice in securities class actions and shareholder derivative litigation. Rosen Law Firm has achieved the largest ever securities class action settlement against a Chinese Company. Rosen Law Firm was Ranked No. 1 by ISS Securities Class Action Services for number of securities class action settlements in 2017. The firm has been ranked in the top 4 each year since 2013 and has recovered hundreds of millions of dollars for investors. In 2019 alone the firm secured over $438 million for investors. In 2020, founding partner Laurence Rosen was named by law360 as a Titan of Plaintiffs’ Bar. Many of the firm’s attorneys have been recognized by Lawdragon and Super Lawyers.

Follow us for updates on LinkedIn: https://www.linkedin.com/company/the-rosen-law-firm, on Twitter: https://twitter.com/rosen_firm or on Facebook: https://www.facebook.com/rosenlawfirm/.

Attorney Advertising. Prior results do not guarantee a similar outcome.

——————————

Contact Information:

Laurence Rosen, Esq.
Phillip Kim, Esq.
The Rosen Law Firm, P.A.
275 Madison Avenue, 40th Floor
New York, NY 10016
Tel: (212) 686-1060
Toll Free: (866) 767-3653
Fax: (212) 202-3827
lrosen@rosenlegal.com
pkim@rosenlegal.com
cases@rosenlegal.com
www.rosenlegal.com

GlobeNewswire Distribution ID 8811638

GLOBALLY RECOGNIZED ROSEN LAW FIRM Encourages Luminar Technologies, Inc. Investors to Inquire About Securities Class Action Investigation – LAZR

NEW YORK, April 19, 2023 (GLOBE NEWSWIRE) — WHY: Rosen Law Firm, a global investor rights law firm, continues to investigate potential securities claims on behalf of shareholders of Luminar Technologies, Inc. (NASDAQ: LAZR) resulting from allegations that Luminar may have issued materially misleading business information to the investing public.

SO WHAT: If you purchased Luminar securities you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement. The Rosen Law Firm is preparing a class action seeking recovery of investor losses.

WHAT TO DO NEXT: To join the prospective class action, go to https://rosenlegal.com/submit-form/?case_id=14243 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action.

WHAT IS THIS ABOUT: On or around March 17, 2023, various media outlets reported that Lidwave, an Israeli start-up, had accused Luminar of attempting to pass off a Lidwave chip as Luminar’s own technology after Luminar displayed an image of the processor at a recent investor conference, as well as in materials on its website. As a result, Lidwave threatened Luminar with legal action. Luminar subsequently removed the images in question from its investor presentation, website, and a YouTube video.

On this news, Luminar’s stock price fell $0.68 per share, or 8%, to close at $7.80 per share on March 20, 2023, the next trading day.

WHY ROSEN LAW: We encourage investors to select qualified counsel with a track record of success in leadership roles. Often, firms issuing notices do not have comparable experience, resources, or any meaningful peer recognition. Many of these firms do not actually litigate securities class actions. Be wise in selecting counsel. The Rosen Law Firm represents investors throughout the globe, concentrating its practice in securities class actions and shareholder derivative litigation. Rosen Law Firm has achieved the largest ever securities class action settlement against a Chinese Company. Rosen Law Firm was Ranked No. 1 by ISS Securities Class Action Services for number of securities class action settlements in 2017. The firm has been ranked in the top 4 each year since 2013 and has recovered hundreds of millions of dollars for investors. In 2019 alone the firm secured over $438 million for investors. In 2020, founding partner Laurence Rosen was named by law360 as a Titan of Plaintiffs’ Bar. Many of the firm’s attorneys have been recognized by Lawdragon and Super Lawyers.

Follow us for updates on LinkedIn: https://www.linkedin.com/company/the-rosen-law-firm, on Twitter: https://twitter.com/rosen_firm or on Facebook: https://www.facebook.com/rosenlawfirm/.

Attorney Advertising. Prior results do not guarantee a similar outcome.

Contact Information:

Laurence Rosen, Esq.
Phillip Kim, Esq.
The Rosen Law Firm, P.A.
275 Madison Avenue, 40th Floor
New York, NY 10016
Tel: (212) 686-1060
Toll Free: (866) 767-3653
Fax: (212) 202-3827
lrosen@rosenlegal.com
pkim@rosenlegal.com
cases@rosenlegal.com
www.rosenlegal.com

GlobeNewswire Distribution ID 8811639

Geneticistas Reprodutivos Reunidos em Paris Apresentam Primeiro Teste de Sequenciamento Completo do Genoma Embriões

  • Dr. Santiago Munné, pioneiro no diagnóstico genético pré-implantação, apresentou o novo teste na Conferência PGDIS
  • Além de detectar genes herdados dos pais, o novo teste de laboratório também revela novas mutações que podem levar a doenças “de novo”, como o autismo.

PARIS, April 19, 2023 (GLOBE NEWSWIRE) — O Dr. Santiago Munné, pioneiro no diagnóstico genético pré-implantação, apresentou o primeiro teste de sequenciamento completo do genoma em embriões para representantes na Preimplantation Genetic Diagnosis International Society (20ª Conferência da Sociedade Internacional de Diagnóstico Genético Pré-implantação – PGDIS), realizada esta semana em Paris.

Em seu discurso no plenário com a presença de mais de 300 especialistas, o Dr. Munné, pioneiro em genética reprodutiva internacionalmente reconhecido, apresentou dados de validação do GenomeScreen™, teste desenvolvido pela equipe de pesquisa liderada por ele na empresa de biotecnologia GenEmbryomics.

“Sabemos desde que começamos a trabalhar com o diagnóstico de embriões em 1993 que a seleção de embriões seria fundamental para a gravidez, especialmente em pacientes mais velhas. Nos últimos 30 anos, nosso trabalho tem se concentrado em aprimorar a seleção genética de embriões, embora a abordagem diagnóstica definitiva – que fornece mais informações e melhores resultados – seja, sem dúvida, esta: sequenciamento completo do genoma do embrião usando apenas algumas células obtidas de uma biópsia. Este teste abre portas que não sabíamos que existiam”, disse Munné sobre o trabalho realizado na GenEmbryomics.

Conhecer o genoma é conhecer um embrião antes da transferência
O GenomeScreen™ é um novo e revolucionário teste de sequenciamento completo do genoma para embriões de fertilização in vitro descrito como “o teste genético mais completo de fertilização in vitro” pelas autoridades do fórum PGDIS.

O teste fornece informações altamente precisas sobre a sequência do genoma do embrião e dos pais genéticos, oferecendo às famílias os principais insights pré-implantação sobre a saúde do embrião e o prognóstico reprodutivo para a tomada decisões bem-informadas. Além disso, essas informações são inestimáveis para pessoas geradas de fertilização in vitro, pois fornecem informações sobre nutrigenômica ou orientação sobre quais medicamentos são mais geneticamente adequados para o paciente.

“Quando começamos nossa pesquisa sobre o sequenciamento de embriões, nosso objetivo era criar uma ferramenta potente e abrangente para que os médicos de fertilidade pudessem acessar dados completos para uma avaliação precisa”, disse o Dr. Nick Murphy, fundador da GenEmbryomics. “Com essa ferramenta usada com 99% de confiabilidade, sabemos que, além de fornecer informações, esse diagnóstico também aumenta substancialmente o sucesso da medicina reprodutiva”, acrescentou Murphy.

O sequenciamento de embriões aumenta o índice de sucesso da fertilização in vitro

O professor Munné, líder em genética reprodutiva de mais de 20 anos, é um importante contribuinte para seleção de embriões e o tratamento de fertilização in vitro. Com este teste, ele e sua equipe de pesquisadores solidificam o papel dos testes genéticos na medicina reprodutiva, aumentando o sucesso do tratamento.

“Os resultados apresentados na conferência são os dados de validação de um teste que irá alterar a forma como a seleção de embriões é realizada”, disse Munné. “A análise genética pré-implantação com sequenciamento completo de genoma é um passo gigantesco: entre outras coisas, informará qual embrião será implantado com sucesso, porque saberemos de antemão qual deles é verdadeiramente saudável – sem doenças herdadas dos pais ou doenças de novo, como o autismo”, conclui ele.

Sobre a GenEmbryomics
Fundada pelo Dr. Nick Murphy em 2019, a GenEmbryomics é uma empresa de biotecnologia de ponta especializada na análise genômica de embriões para determinar os candidatos mais viáveis para a implantação de fertilização in vitro. Seu trabalho proporcionará índices de maior sucesso nos ciclos de fertilização in vitro, graças aos seus algoritmos proprietários que oferecem uma seleção de embriões mais precisa e eficiente, com base em todo o genoma de cada embrião.

Para mais informação
Dulce Iborra Candela
+34 647942875
dulce@laembajadora.es

GlobeNewswire Distribution ID 8811736

Les généticiens de la reproduction réunis à Paris présentent le tout premier test de séquençage du génome entier dans des embryons

  • Le Dr Santiago Munné, un pionnier du diagnostic génétique préimplantatoire, a présenté le nouveau test lors de la Conférence PGDIS
  • Non seulement ce nouveau test de laboratoire détectera les gènes hérités des parents, mais il révèlera également les nouvelles mutations pouvant mener à des maladies « de novo » comme l’autisme

PARIS, 20 avr. 2023 (GLOBE NEWSWIRE) — Le Dr Santiago Munné, pionnier du diagnostic génétique préimplantatoire, a présenté le premier test de séquençage du génome entier sur des embryons devant les participants à la 20e Conférence de la Société internationale de diagnostic génétique préimplantatoire (PGDIS pour Preimplantation Genetic Diagnosis International Society), organisée cette semaine à Paris.

Lors de son allocution plénière à laquelle ont assisté plus de 300 experts, le Dr Munné, un précurseur de la génétique de la reproduction de renommée internationale, a présenté des données de validation pour GenomeScreen™, le test développé par l’équipe de recherche qu’il dirige dans la société de biotechnologie GenEmbryomics.

« Nous savions, depuis que nous avons commencé à travailler sur le diagnostic embryonnaire en 1993, que la sélection embryonnaire serait déterminante pour la grossesse, surtout chez les patientes plus âgées. Au cours des 30 dernières années, notre travail s’est concentré sur l’amélioration de la sélection embryonnaire génétique, même si l’approche diagnostique définitive (celle qui fournit le plus d’informations et les meilleurs résultats) sera sans aucun doute celle-ci : le séquençage du génome entier de l’embryon à l’aide de quelques cellules seulement obtenues à partir d’une biopsie. Ce test va ouvrir des portes dont nous ignorions jusqu’à l’existence », a déclaré le Dr Munné sur le travail accompli chez GenEmbryomics.

Comprendre le génome, cela signifie tout savoir sur un embryon avant le transfert
GenomeScreen™ est un nouveau test révolutionnaire sur le séquençage du génome entier pour les embryons issus de FIV, qui a été décrit par les autorités comme « le test génétique le plus complet dans la FIV » lors du forum PGDIS.

Le test apporte des renseignements extrêmement précis sur la séquence du génome de l’embryon et sur les parents génétiques, fournissant aux familles des informations préimplantatoires déterminantes sur la santé de l’embryon et le pronostic de reproduction pouvant éclairer leurs décisions. Par ailleurs, ces informations seront inestimables pour les personnes nées d’une FIV, car elles fourniront des données sur la nutrigénomique ou des conseils sur les médicaments les plus génétiquement adaptés au/à la patient(e).

« Au tout début de nos recherches sur le séquençage d’embryons, notre objectif était de créer un outil complet et puissant, qui pourrait doter les médecins de la fertilité de données exhaustives pour des dépistages de précision », s’est souvenu le Dr Nick Murphy, fondateur de GenEmbryomics. « Maintenant que nous avons cet outil et que nous l’utilisons avec une fiabilité de 99 %, nous avons conscience que ce diagnostic nous fournit des informations, mais améliore également considérablement le succès de la médecine de reproduction », a ajouté le Dr Murphy.

Le séquençage des embryons va augmenter les taux de réussite des FIV

Le professeur Munné, dont la carrière en tant que chef de file en génétique reproductive s’étend sur plus de 20 ans, a apporté d’énormes contributions à la sélection embryonnaire et au traitement de FIV. Avec ce test, lui et son équipe de chercheurs solidifient le rôle des tests génétiques dans la médecine de reproduction, augmentant le succès des traitements.

Selon le professeur Munné : « Les conclusions présentées lors de la conférence constituent les données de validation d’un test qui va changer la sélection embryonnaire telle que nous la connaissons ». « L’analyse génétique préimplantatoire avec séquençage du génome entier représente un pas de géant : entre autres choses, elle nous dira quels embryons s’implanteront avec succès, car nous saurons à l’avance lesquels sont vraiment en bonne santé, c’est-à-dire sans maladie héritée des parents ou sans maladie de novo, comme l’autisme », a-t-il conclu.

À propos de GenEmbryomics
Fondée par le Dr Nick Murphy en 2019, GenEmbryomics est une société de biotechnologie de pointe spécialisée dans l’analyse génomique des embryons afin de déterminer les candidats les plus viables pour une implantation par FIV. Son travail conduira à des taux de réussite plus élevés dans les cycles de FIV, grâce à ses algorithmes propriétaires qui permettent une sélection embryonnaire plus précise et plus efficace, basée sur le génome entier de chaque embryon.

Pour tout complément d'information
Dulce Iborra Candela
+34 647942875
dulce@laembajadora.es

GlobeNewswire Distribution ID 8811736